Interviews with regulators, including ECHA and national regulators on how they see the role and potential of QSAR models within REACH.
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ORCHESTRA is an EU project, funded to disseminate recent research on computer-based in silico methods for evaluating the toxicity of chemicals.
•• In silico methods make it possible to test large numbers of chemicals (as required by EU REACH legislation) while reducing the numbers of tests on animals.
The aim of the project is therefore to promote wider understanding, awareness and appropriate use of in silico methods.
Why does industry need to know about in silico methods?
The REACH legislation puts the responsibility on industry to provide the necessary toxicity information on each substance which they manufacture, distribute and market, and to assess and manage the risks linked to those substances. This is the principle of ‘no data, no market’. Industry are therefore a key stakeholder in influencing the future use of in silico methods.
For further information, see the page ‘Why use in silico methods?’ on this site. It outlines why industry needs to use in silico methods, or at least know about them.
An interview with Professor Wim de Coen, Head of Evaluation 1 at the European Chemicals Agency (ECHA), on 30 June 2010.
With special thanks to Wim de Coen.