The REACH legislation
In December 2006 the European Community adopted a new regulation addresses the production circulation of chemical substances in the European territory, and their potential impacts on both human health and the environment. This new regulation is called REACH (Registration, Evaluation, Authorisation and restriction of Chemicals) and states that for each chemical circulating in the European territory, a complete dossier on physico-chemical, biological and toxicological properties has to be compiled. In order to prevent an over-usage of animal testing, REACH regulation foresees and promotes the use of alternative methods (such as QSAR) stating that:
Before new tests are carried out to determine the properties listed in this Annex, all available in vitro data, in vivo data, historical human data, data from valid (Q)SARs and data from structurally related substances (read-across approach) shall be assessed first.
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