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QSARs in REACH? - Uses, issues and priorities

A video documentary in four parts, based on interviews
with regulators, industry and QSAR developers.

Watch the documentary

ORCHESTRA Workshop: REACH and QSAR - What can we learn from case studies?

Milan, 6 April, 2011

View the report on the outcomes

Help to guide our work - respond to a short survey

technical survey - on your experience and view of computer-based methods in toxicology
public survey - on reducing animal testing and other issues.

Visit Surveys page

21st ANNUAL MEETING - SETAC EUROPE

ECOSYSTEM PROTECTION IN A SUSTAINABLE WORLD
a Challenge for Science and Regulation
15 - 19 May 2011, Milan, Italy

Learn more

Introductory leaflet on in-silico methods

for people who want to know about in-silico methods
and/or to understand what the ORCHESTRA project is about

Download the leaflet

ORCHESTRA

In Silico Software and Resources

DEMETRA

DEMETRA developed QSAR models for ecotoxicology, specific for pesticides and related compounds.

QSAR models have been developed for:

Trout
Daphnia
Bee
Quail (oral esposure)
quail (dietary esposure)

Some good results (poster) have been obtained also on industrial chemicals, in particular for the chemicals with a complex structure which escape correct prediction with models like EPISUITE.

The user should calculate chemical descriptors first, and then use DEMETRA.