Many QSAR models have been developed and some are publicly available. Depending on the purpose different models should be used. For instance, for REACH certain requirements have been defined (link to above). For regulatory purposes transparency is highly preferred, in order to provide full information on the model. This also complies with the OECD principles (link). As a consequence, the user should verify if full details on the model are available. For commercial models there may be limitations.
These are some examples of publicly available models developed within the EC projects evaluated within ORCHESTRA.
Benefits and barriers to the use of computer-based methods: Online Survey and Report
In recent years the EU have funded research into developing QSAR / In Silico(i.e. computer-based) methods for the evaluation of chemical toxicity. This project is intended to communicate those findings so that the research is used more widely. The online survey will help us to find out what information is needed.