The report of our online stakeholder survey is available here. Learn about benefits and barriers to QSARs use according to specialists, regulators and industry.
The results of this survey have been published in the open access literature as follow:
Mays C, Benfenati E and Pardoe S.
Use and perceived benefits and barriers of QSAR models for REACH: findings from a questionnaire to stakeholders
Chemistry Central Journal 2012, 6:159 doi:10.1186/1752-153X-6-159
The REACH legislation requires industry to evaluate the toxicity not just of new chemicals, but also of the tens of thousands of existing chemical substances that are currently in use but have never been subject to regulatory testing. Many argue that to achieve this by traditional in vivo testing would take decades, cost billions and consume many millions of vertebrates. In addition to the time and costs for industry, there is a lack of laboratories in Europe capable of performing in vivo tests for such large numbers of substances.
The short questionnaire is our invitation to policy makers, industry managers, educators, political leaders, NGOs, investors, citizens and all others who are not specialists in toxicology to comment on some of the issues that are raised and/or addressed by computer-based (in silico) methods.
We really hope you can take a few minutes to complete it. Please also email the link to others who may be interested.
The ORCHESTRA layman's report, entitled "Improving realistic use of in silico methods", gives an overview of the most significant resources developed by ORCHESTRA for people involved or interested in the use of in silico methods in REACH.
Each resource is briefly explained and the readers are provided with links or information about where they can download it or find more about it. This report has been developed with users’ needs in mind and together with the ORCHESTRA website, the introductive leaflet and the e-book is an important source of information.
The e-book "Theory, guidance and applications on QSAR and REACH" has been developed with the aim of providing an accessible source of information about in silico models and their use in toxicology for regulatory purposes.
The leaflet is intended as a concise and accessible explanation of in silico methods, and the issues around them, for people who want to know about them, and/or what to understand what the ORCHESTRA project is about.
The leaflet is available in English, French, German and Italian languages.